Featured in Domain Arrivals · 2026-08-12
Lit2Bench — cryptic splicing, from RNA-seq to the bench
A free, open-source macOS toolkit that detects cryptic splicing in RNA-seq data, designs validation assays, and keeps the workflow together through lab results and notebook records.
Why it surfacedLit2Bench connects eighteen handoff-ready tools, from BAM analysis and transcript exploration to primer design, plasmid QC, and an ordering sheet. It runs locally, keeps data on the user's Mac, uses deterministic calculations and named scientific references, and even treats its optional language-model step as an offline, tightly limited component.
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Ice Does Not Count
August 12’s newborn domains include a rule-bound archive of enormous sodas, 27 family stories cut from one afternoon, a disaster-supply map with a 24-hour freshness rule, and an ocean bell that rings only when six conditions agree.
This is one of 1,000 discoveries in the 2026-08-12 Domain Arrivals issue.