Observed arrival · 2026-09-03
ResonatE: A Smaller Orchestra for Drug–Disease Reasoning
ResonatE is a biomedical knowledge-graph embedding model that uses compact matrix operators to connect drugs, diseases, and genes.
Field notes
ResonatE represents entities as vectors in a 144-dimensional complex space and relations as free 4×4 block operators, making a multi-hop query a chain of small matrix operations followed by one lookup. The page reports 27,124,129 parameters and compares the complex formulation with an equivalent real-valued version. Its benchmark claims cover drug, disease, and gene relationships in ogbl-biokg, while a larger ogbl-wikikg2 run is presented as a dress rehearsal rather than a completed leaderboard result.
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