Feng Lab Explains DNA Replication, One Molecular Machine at a Time

Field notes

The page uses a numbered molecular narrative rather than a conventional lab-site structure: visitors follow the lagging strand through primer placement, clamp loading, elongation, primer removal, and ligation. It names the relevant machinery, including CMG, RPA, RFC, PCNA, Pol δ, RNase H, FEN1, and ligase, while noting that particle sizes, primer lengths, quantities, and timing are schematic. The research section connects this explanation to epigenetics, genome stability, and replication stress.