Observed arrival · 2026-09-13
The Human TF Binder Atlas
An interactive atlas of human transcription factors with reported small-molecule binding below 1 µM.
Field notes
The atlas applies a below-1-µM binding threshold using Kd or Ki measurements and organizes results by transcription-factor class, disease evidence, and clinical status. Its starting reference is the Lambert catalogue of human TFs, version 1.01, with nuclear receptors handled through a visible inclusion toggle. Selected factors can expose compounds, measurements, and supporting sources, while a download control offers the current evidence data. The page explicitly separates direct binding evidence from functional activity, safety, and drug potential.
Observed signals
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