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Card 784 of 9722026-09-25 issue

Observed arrival · 2026-09-25

StruPair sorts protein structures into five relationship classes

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Editorial interest 77/100 Selection signal · not a rating of the site

A browser-based tool that compares two protein backbone structures and assigns their relationship to one of five ordered classes.

Landing page captured for the 2026-09-25 issue.
For
Researchers comparing pairs of protein conformations
Worth noticing
It accepts PDB or mmCIF uploads up to 2 MB total per request and asks for a chain ID in each structure.

Field notes

The form requires one chain identifier per structure: label_asym_id for mmCIF and the recorded chain ID for PDB. Requests are limited to 2 MB total, and the site says uploaded temporary files are deleted after each request. Its five classes run from global reorganization through coherent region movement to small structural variation; the page cautions that reported probabilities are uncalibrated and do not represent transition rates or energy barriers.

Observed signals

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Editorial observations of this landing page, not a rating.

○OpenPublic substance visible
✦PrettyNotable craft visible
◎NicheUnusually specific use

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strupair.org

Landing page observed 2026-09-25. The live site may have changed.