Observed arrival · 2026-09-27
Triangulation Research: when study designs disagree
An epidemiology research project examines what disagreements between study designs and diagnostic criteria reveal about what each one measures.
- For
- Epidemiology and diagnostic-methods researchers
- Worth noticing
- For 309 multiple-sclerosis patients, two diagnostic rules changed the reported disability rate within the diagnosed group from 46% to 27%.
Field notes
The project frames disagreement as evidence about measurement, rather than treating it as a nuisance to average away. Its homepage gives short result summaries across several research areas, including a comparison of diagnostic rules in a 309-patient MS cohort and an analysis of pooled site-level estimates against patient-level effects across 42 million COVID-19 records. The linked papers may provide further methods and context, but their access conditions are not visible here.
Observed signals
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Editorial observations of this landing page, not a rating.
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