Observed arrival · 2026-10-10
LCMSER: A field guide for LC-MS problems
A free set of LC-MS troubleshooting guides and calculators for people who run or develop methods on the instruments.
- For
- LC-MS operators, core-facility staff, and method developers
- Worth noticing
- The disclaimer says reference values are estimates, not a substitute for manufacturer manuals, lab SOPs, or safety procedures.
Field notes
The listed troubleshooting areas include sensitivity, pressure, carryover, background, peak shape, and retention drift; the mass-spectrometry calculators name ppm error, XIC windows, and adduct masses. Method-development utilities are described as covering column-volume scaling and dilution tables. The owner says the resource is independent of instrument manufacturers and warns that its reference values are general estimates, not a substitute for manuals, lab SOPs, or safety procedures.
Observed signals
Read the marks
Editorial observations of this landing page, not a rating.
One card from the complete issue