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2026-10-21 issue

Observed arrival · 2026-10-21

The Aortic Stenosis Instability Index

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A research calculator estimates how likely an aortic-stenosis severity label is to change on a short-interval repeat echocardiogram.

Landing page captured for the 2026-10-21 issue.
For
Healthcare professionals assessing aortic-stenosis echocardiograms
Worth noticing
The page says its measurement-variability data comes from 607 patients with paired echocardiograms within six months across two centres.

Field notes

The input fields are peak velocity, mean gradient, and valve area; sample links provide stable-severe, fragile-moderate, and borderline-low-gradient cases. The page describes 4,000 simulated repeats and a covariance matrix of between-study differences, attributed to 607 patients with paired transthoracic echocardiograms within six months across two centres. Its stated thresholds distinguish high-gradient severe, discordant low-gradient severe, and moderate classifications.

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asinstabilityindex.org

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