Observed arrival · 2026-11-12
Brain is Time: Alzheimer’s as a dynamic system
A research-led presentation argues that Alzheimer’s symptoms should be understood through disrupted brain-network dynamics, not pathology and structural loss alone.
- For
- Readers following Alzheimer’s research and neuroscience
- Worth noticing
- The page says activity-driven pathology is supported experimentally, while evidence for that link in patients remains largely correlational.
Field notes
The argument is attributed to Willem de Haan, MD PhD, of Alzheimer Center Amsterdam and the Department of Neurology at Amsterdam UMC. It uses ventricular fibrillation and a scarred heart to illustrate why organ function can fail through disrupted dynamics even when structure alone does not explain the outcome. The page distinguishes experimental findings about neuronal activity from the more limited, largely correlational evidence in patients.
Observed signals
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