Horvath Lab and the Measurement of Biological Age

Field notes

The lab develops mathematical clocks from chemical marks on DNA, then examines whether a measured age change reflects underlying biology or merely a shifted marker. Its stated research crosses human tissues and other mammals, including mice, bats, and whales, and follows a chronology from a saliva-based clock in 2011 to a multi-tissue clock in 2013 and a pan-mammalian clock in 2023. The site also emphasizes measurement precision as a prerequisite for clinical or regulatory use.