Observed arrival · 2026-08-24
The Peptide That Tells Mitochondria to Hold
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Panacea Bio Chem’s HDAP2 dossier explains a mitochondria-targeted peptide studied after optic-nerve injury in mice.
Field notes
The dossier identifies HDAP2 as Biotin–dArg–Phe–Phe–dArg–amide and assigns separate roles to its D-arginine ends, Phe-Phe core, and terminal amide. Its study summary covers optic-nerve crush in C57BL/6 mice, daily systemic dosing, retinal regions, mitochondrial ultrastructure, and axonal degeneration. The page reports nearly threefold mitochondrial density versus untreated crushed nerves, while explicitly distinguishing prevention of loss from repair of damaged organelles.
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